解读《加拿大二膦酸盐相关性下颌骨坏死诊疗指南共识》.pdf

·cr?· 4T???:100029　9N?,?°?azcD??Açcf S uY?4T?:??j,Email:[email protected] ?《iF&EvmL?Ö?tMaV? tS?ap?µ?ht?2aqM》 周惠琼 ?umms Ëa|:R246.83　　?tD9SM’:A　　?Rc9Ia|:1006-7108(2009)03-0236-05 RKcV:Û4bmL?Ö?aFmW?????htap?¾?、mW???tMaV?ap?id9h?,mL?Ö??zt?tS ?ap?µ(ONJ)?iv?zt¦Ì?aV?,ñ^cB?ahinmI???9im??。?EN,iF&Ev g8ig?ë? S ??4F?h8aS=??me? S4EiE,uYaVm6ONJtMaV??tD??h8tbud??tn,??h8mL?Ö?tMaV ?ONJ?ht?2。"??"EGcD3uYa0cB??mu、?m]ig?htmL?Ö?tMaV?ONJ?iycp。9K?mJ crh8?2aqM?tMaV=¸,a0"EGcD3? I。 aVioEM:ap?µ;tS?ap; ?Ö? Explanationof“CanadianConsensusPracticeGuidelinesforBisphosphonateAssociatedOsteonecrosisofthe Jaw”　ZHOUHuiqiong.RheumatologyandImmunologyDepartment,China-JapanFriendshipHospital,Beijing 100029,China Abstract:Osteoporosisisbecomingmorecommonnowadays.Bisphosphonateshavebecomeacornerstoneinthe managementofosteoporosis,skeletalcomplicationsofmalignancyandothermetabolicbonedisease.Thoughthese agentsoffergreatbenefittothosewithmalignancyormetabolicbonedisease,therearesomesideeffectsreported regardingbisphosphonate-associatedosteonecrosisofthejaw(ONJ).TheCanadianAssociationofOraland MaxillofacialSurgeons(CAOMS)inassociationwithnationalandinternationalsocietiesreviewedthecurrent referenceofONJassociatedwithbisphosphonateanddevelopedrecommendationsregardingdiagnosis,identification ofat-riskpatients,preventionandmanagementstrategiesofONJcausedbybisphosphonates.Wehereprovided partialtranslationinChinesefromtheoriginalpaper. Keywords:Osteonecrosis;Jaw;Bisphosphonate 　　4VEV2003M?cB èaV?mL?Ö??zttS?ap ?µ(osteonecrosisofthejaw,ONJ)?9R?m?9V?,mL ?Ö?tMaV?ONJ 7S?ztcD???aV?,ONJ^ mL?Ö????ahinmI????9im??,"-?aV ñ?m?9hit Ø?????o4。 ?iTM,mL?Ö?aFmW??ap?¾、mW??? tMaV?ap?id9hig????,m6?ap?¾???, tliYhi?mL?Ö???tr???44uUigmd44uU?ap R|?tB,mL?Ö???? Vc[ª^?ht??tMaV? ap?id9higap?¾? Ú?97。?RnmeM?"EG? ??,m?tCcBtt??